Niacin CRT™ 500 mg NE contains 500 mg of NE niacin (as nicotinic acid) in a unique wax-matrix tablet that utilizes the latest controlled-release technology (CRT). This technology delivers niacin in a continuous, controlled rate over a 6 to 8 hour period throughout the tablet’s transit time in the bowel. Flushing sometimes happens with time-release niacin, as there can be fairly large surges of niacin released intermittently. However, flushing is less likely with controlled-release niacin. This product may be beneficial for healthy lipid management.* Recommended Use: Take one tablet per day with a meal or as directed by your health-care practitioner. Do not crush tablets. Warning:Niacin may cause temporary flushing, itching, or tingling sensations. If you are pregnant or nursing, consult your health-care practitioner before taking this product.