5-MTHF ES provides 17,000 mcg of 5-MTHF (5-methyltetrahydrofolate) per serving. 5-MTHF is the most biologically active form of the water-soluble B vitamin, folate;  and it may be the preferred form for those with variations in digestion, absorption, or folate metabolism. Data suggest that in comparison to synthetic folic acid, 5-MTHF increases plasma folate more effectively. In this formula, 5-MTHF is provided as Quatrefolic^®—the glucosamine salt of 5-MTHF. Quatrefolic has demonstrated greater stability, solubility, and bioavailability when compared to calcium salt forms of 5-MTHF.*

• Supports Healthy Serum Folate*
• Supports the Conversion of Homocysteine to Methionine*
• Supports Methylation*
• Supports Nervous System and Oral Health*
• Supports Normal Cellular Proliferation (including red blood cells)*
• Supports a Healthy Pregnancy Outcome*

Suggested Use:
Take one to two capsules daily, or as directed by your healthcare professional. 

Serving Size: 2 Capsules

Amount Per Serving
Folate … 17,000 mcg DFE
(as (6S)-5-methyltetrahydrofolic acid, glucosamine salt)

Other Ingredients: Microcrystalline cellulose, capsule (hypromellose and water), stearic acid, magnesium stearate, and silica.

Formulated to Exclude: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.