Ultra B12-Folate is a unique formula that combines vitamin B12 (cobalamin) with the patented folate derivative, Quatrefolic®. These two vitamins work synergistically, improving methylation and helping to promote balanced concentrations of homocysteine.* Although many manufacturers offer these separately, Designs for Health's formula offers the convenience of getting both B vitamins in one capsule. The premium B12 in this product comes from equal amounts of adenosylcobalamin and methylcobalamin. Recommended Use: Take 1 capsule per day with a meal or as directed by your health-care practitioner. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.